GIANT 2018 Body Fat Distribution exome chip analysis: European females
This dataset is a subset of the GIANT 2018 Body Fat Distribution exome chip analysis dataset.
ExTexT2D exome chip analysis: Europeans
This dataset is a subset of the ExTexT2D exome chip analysis dataset.
Note that the samples in the GoT2D exome chip analysis and FUSION exome chip analysis datasets are a subset of those included in the ExTexT2D exome chip analysis dataset. Cases in the EXTEND GWAS dataset are included in the ExTexT2D exome chip analysis dataset.
Hypertension exome chip analysis: Europeans
This dataset is a subset of the Hypertension exome chip analysis dataset.
Publications
Trans-ancestry Meta-Analyses Identify Rare and Common Variants Associated With Blood Pressure and Hypertension.
Surendran P, et al.
Nat Genet. 2016 Oct; 48(10): 1151–1161. doi: 10.1038/ng.3654
PMID:27618447
Combined EGLs method
The ultimate goal of genetic association studies is to discover which genes and pathways have direct roles in risk of a disease or trait. Several methods now combine genetic association results with multiple kinds of evidence to generate lists of the genes that are most likely to mediate the genetic associations. The Knowledge Portals currently host results from three such methods that predict type 2 diabetes effector genes. The methods differ in the evidence types that they use as input and in the classifications or scores that they generate.
PGC bipolar disorder GWAS
Dataset
Summary statistics are available for download at the Psychiatric Genomics Consortium website.
Publications
Genome-wide association study identifies 30 loci associated with bipolar disorder.
Stahl EA, et al.
Nat Genet. 2019 May;51(5):793-803. doi: 10.1038/s41588-019-0397-8.
PMID:31043756
PGC major depressive disorder GWAS
Dataset
Summary statistics are available for download at the Psychiatric Genomics Consortium website.
Publications
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Wray NR, et al.
Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3.
PMID:29700475
Late-onset Alzheimer's GWAS
Dataset
Summary statistics are available for download at the GWAS Catalog.
Publications
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Kunkle BW, et al.
Nat Genet. 2019 Mar;51(3):414-430. doi: 10.1038/s41588-019-0358-2.
PMID: 30820047
GR@CE Alzheimer's GWAS
Dataset
Summary statistics are available for download at the GWAS Catalog.
Publications
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
Moreno-Grau S, et al.
Alzheimers Dement. 2019 Oct;15(10):1333-1347. doi: 10.1016/j.jalz.2019.06.4950.
PMID:31473137
COVID-19 Host Genetics Initiative Round 4 GWAS: D1 analysis
Dataset
This dataset is part of the COVID19-hg GWAS meta-analyses round 4, released on October 20, 2020.
PublicationsTitle.
First author, et al.
Citation
PMID:nnn
COVID-19 Host Genetics Initiative Round 4 GWAS: C2 analysis, Europeans
Dataset
This dataset is part of the COVID19-hg GWAS meta-analyses round 4, released on October 20, 2020.
PublicationsTitle.
First author, et al.
Citation
PMID:nnn