Hypertension exome chip analysis: Europeans

This dataset is a subset of the Hypertension exome chip analysis dataset.

Publications

Trans-ancestry Meta-Analyses Identify Rare and Common Variants Associated With Blood Pressure and Hypertension.
Surendran P, et al.
Nat Genet. 2016 Oct; 48(10): 1151–1161. doi: 10.1038/ng.3654
PMID:27618447

Dataset phenotypes

• Diastolic blood pressure
• Hypertension
• Pulse pressure
• Systolic blood pressure

Experiment summary

This study analyzed genetic associations with hypertension and related blood pressure phenotypes in subjects of European (EUR) ancestry (up to 165,276 individuals), after which a trans-ethnic meta-analysis of the European and additional South Asian ancestry subjects (up to 192,763 individuals) was performed. Both the European subset and the overall meta-analysis are integrated into the Portal.