The Human Genetics Amplifier (HuGeAMP) is a software platform and infrastructure that aggregates, integrates, and analyzes human genetic and genomic data in order to spark insights into complex diseases.

The Knowledge Portal Network (KPN) is an ecosystem of interconnected web portals that facilitate innovative and intuitive analysis and visualization of biomedical data. The Knowledge Portals that are based on human genetic association data are powered by the HuGeAMP platform.

The Knowledge Portals:

  • aggregate comprehensive data relevant to diseases and traits;

  • harmonize and analyze the data;

  • represent the data in a way that helps researchers to distill meaning from them; and

  • provide interactive tools for custom analyses that access individual-level data in a secure manner.

We welcome collaborations that augment the existing portals of the Knowledge Portal Network or expand the network to more areas of biology. There are several ways to get involved:

Contribute to the HuGeAMP platform: help to implement new methods for integrating and analyzing genetic and genomic data.

Contribute results to the existing Knowledge Portals: in disease areas relevant to the Knowledge Portals listed below, we can host and incorporate your large-scale genetic or genomic datasets, effector gene predictions, and more. Find more details here.

Collaborate with us to create a new Knowledge Portal: if you have resources to support a collaboration to build a full-scale Knowledge Portal, our team can work with you to develop a portal in a biomedical area that is new to the KPN.

Create a standalone Research Data Page or Research Data Portal for your results: our Bring Your Own Results (BYOR) service lets you quickly and easily create a single web page or a multi-page portal to display your results with interactive tables and graphics. See examples in the Research Data Pages and Portals section below, and find details on the BYOR service here.

Contact us to discuss these opportunities: help (at) kp4cd.org.

 

Knowledge Portal Network

Common Metabolic Diseases Knowledge Portal
Visit portal
Cardiovascular Disease Knowledge Portal
Visit portal
Cerebrovascular Disease Knowledge Portal
Visit portal
Sleep Disorder Knowledge Portal
Visit portal
Type 1 Diabetes Knowledge Portal
Visit portal
Type 2 Diabetes Knowledge Portal
Visit portal
Musculoskeletal Knowledge Portal
Visit portal
ALS Knowledge Portal
Visit portal
Lung Disease Knowledge Portal
Visit portal
Lipid Droplet Knowledge Portal
Visit portal

Research Data Pages and Portals

The APOL1 Portal
Visit portal
Catalog of vQTLs and GxEs for cardiometabolic biomarkers
Visit portal
Genetic Loci Clustering
Visit portal
Curated T2D effector gene predictions
Visit portal
Coronary artery disease effector gene predictions
Visit portal
Effector index predictions
Visit portal
Integrated Classifier T2D effector predictions
Visit portal

What's new

The Foundation for the National Institutes of Health is releasing four open-competition funding opportunities for the Accelerating Medicines Partnership® in Common Metabolic Diseases.
In our December 9, 2021 webinar we introduced and demonstrated our new "Bring Your Own Results" (BYOR) interactive interface.
On Thursday, December 9th we'll present a webinar introducing the BYOR service that allows researchers to quickly and easily visualize and share their results.