Dataset
Summary statistics are available for download at the GWAS Catalog.
Publications
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Kunkle BW, et al.
Nat Genet. 2019 Mar;51(3):414-430. doi: 10.1038/s41588-019-0358-2.
PMID: 30820047
Phenotypes
- Late-onset Alzheimer's disease
Subjects
| Cases | Controls | Consortium | Ancestry |
|---|---|---|---|
| 14,428 | 14,562 | Alzheimer Disease Genetics Consortium (ADGC) | European |
| 2,137 | 13,474 | Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) | European |
| 2,240 | 6,631 | European Alzheimer’s Disease Initiative (EADI) | European |
| 3,177 | 7,277 | Genetic and Environmental Risk in AD (GERAD) | European |
Experiment summary
This study analyzed genetic associations with late-onset (after 65 years of age) Alzheimer's disease in 21,982 cases and 41,944 controls.
Dataset ID
Kunkle2019_Alzheimers_eu