Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
Nagy R, et al.
Genome Med. 2017; 9: 23. doi: 10.1186/s13073-017-0414-4.
PMID:28270201
Download summary statistics: alcohol consumption, BMI, body fat percentage, diastolic blood pressure, pulse pressure, systolic blood pressure, serum urea, serum urate, total cholesterol, serum creatinine, fasting plasma glucose in diabetics and non-diabetics.
Download summary statistics: waist-hip ratio, height, heart rate, HDL cholesterol, fasting plasma glucose (non-diabetics).
Exome Sequencing in Amyotrophic Lateral Sclerosis Implicates a Novel Gene, DNAJC7, Encoding a Heat-Shock Protein
Farhan SMK, et al.
Nat Neurosci. 2019 Dec; 22(12): 1966–1974. doi: 10.1038/s41593-019-0530-0
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
van Rheenen W, et al.
Nat Genet. 2016 Sep;48(9):1043-8. doi: 10.1038/ng.3622
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
van Rheenen W, et al.
Nat Genet. 2016 Sep;48(9):1043-8. doi: 10.1038/ng.3622
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Onengut-Gumuscu S, et al.
Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245.
PMID:25751624
test content
These predictions synthesize multiple kinds of biological evidence to classify genes that are most likely to have direct roles in T2D risk and may represent potential drug targets. The “Combined prediction” column contains the classification of each gene’s potential to be causal based on the evidence contained in the table, as determined by Anubha Mahajan and Mark McCarthy. The classifications for potential T2D effectors are "Causal", "Strong", "Moderate", "Possible", and "Weak".
Full documentation is available in:
Summary statistics are available for download at the GWAS Catalog.
Insights Into the Aetiology of Snoring From Observational and Genetic Investigations in the UK Biobank.
Campos AI, et al.
Nat Commun 2020 Feb 14;11(1):817. doi: 10.1038/s41467-020-14625-1.
PMID:32060260