FinnMetSeq exome sequence analysis: WHR adj BMI associations, females
Dataset
This dataset is a subset of the FinnMetSeq exome sequence analysis dataset.
Publications
Exome sequencing of Finnish isolates enhances rare-variant association power.
Locke A, Meltz Steinberg K, Chiang, CWK, Service S, et al.
Nature. 2019 Jul 31. doi: 10.1038/s41586-019-1457-z
AMP T2D-GENES T2D exome sequence analysis: trans-ancestry
The 13k exome sequence analysis dataset is a subset of the AMP T2D-GENES exome sequence analysis dataset.
GoT2D exome chip analysis
Dataset
Note that the samples in the GoT2D exome chip analysis and FUSION exome chip analysis datasets are a subset of those included in the ExTexT2D exome chip analysis dataset.
Publications
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Flannick J, Fuchsberger C, Mahajan A, et al.
Sci Data. 2017 Dec 19;4:170179. doi: 10.1038/sdata.2017.179
SIGMA exome chip analysis
Downloads
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Publications
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Mercader M, et al.
Diabetes 2017 Nov;66(11):2903-2914. doi: 10.2337/db17-0187.
PMID:28838971
GLGC exome chip analysis
Publications
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.
Lu X, et al.
Nat Genet. 2017 Dec;49(12):1722-1730. doi: 10.1038/ng.3978.
GIANT 2018 Body Fat Distribution exome chip analysis
Publications
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Justice AE, et al.
Nat Genet. 2019 Mar;51(3):452-469. doi: 10.1038/s41588-018-0334-2
GIANT 2018 BMI, Height exome chip analysis
Dataset
Publications
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Turcot V, et al.
Nat Genet. 2018 Jan;50(1):26-41. doi: 10.1038/s41588-017-0011-x
FUSION exome chip analysis
Dataset
Note that the samples in the GoT2D exome chip analysis and FUSION exome chip analysis datasets are a subset of those included in the ExTexT2D exome chip analysis dataset.
ExTexT2D exome chip analysis
Dataset
Note that the samples in the GoT2D exome chip analysis and FUSION exome chip analysis datasets are a subset of those included in the ExTexT2D exome chip analysis dataset. Cases in the EXTEND GWAS dataset are included in the ExTexT2D exome chip analysis dataset.