Dataset
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Publications
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.
Wu P, et al.
PLoS One 2020 May 7;15(5):e0230815. doi: 10.1371/journal.pone.0230815.
PMID:32379818
Dataset phenotypes
- Smoking-fasting glucose interaction
- Smoking-fasting glucose interaction, joint 2-degree-of-freedom test
- Smoking-fasting glucose interaction, main effect model
- Smoking-T2D interaction
- Smoking-T2D interaction, joint 2-degree-of-freedom test
- Smoking-T2D interaction, main effect model
Dataset subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 2,358 | Atherosclerosis Risk in Communities Study (ARIC) | African American |
| 1,024 | Coronary Artery Risk Development in Young Adults Study (CARDIA) | African American |
| 134 | Cardiovascular Health Study (CHS) | African American |
| 1,308 | Multi-Ethnic Study of Atherosclerosis (MESA) | African American |
Experiment summary
This study is a gene-environment-wide interaction study (GEWIS) to identify potential gene-by-smoking interactions for incident type 2 diabetes and baseline fasting glucose. In the Portal, associations from this study are displayed in 5 datasets:
- Smoking-genotype interaction for T2D and FG: African Americans
- Smoking-genotype interaction for T2D and FG: Europeans
- Smoking-genotype interaction for T2D and FG: African Americans, ever-smokers
- Smoking-genotype interaction for T2D and FG: Europeans, ever-smokers
- Smoking-genotype interaction for T2D and FG: African Americans, never-smokers
- Smoking-genotype interaction for T2D and FG: Europeans, never-smokers
Dataset ID
GWAS_SmokingT2D_aa