Combined EGLs method

Submitted by dkjang on

The ultimate goal of genetic association studies is to discover which genes and pathways have direct roles in risk of a disease or trait. Several methods now combine genetic association results with multiple kinds of evidence to generate lists of the genes that are most likely to mediate the genetic associations. The Knowledge Portals currently host results from three such methods that predict type 2 diabetes effector genes. The methods differ in the evidence types that they use as input and in the classifications or scores that they generate.

GR@CE Alzheimer's GWAS

Dataset

Summary statistics are available for download at the GWAS Catalog.

Publications

Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
Moreno-Grau S, et al.
Alzheimers Dement. 2019 Oct;15(10):1333-1347. doi: 10.1016/j.jalz.2019.06.4950.
PMID:31473137