MAGIC modified Stumvoll ISI GWAS
Publications
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.
Walford G, Gustafsson S, Rybin D, et al.
Diabetes. 2016 Oct;65(10):3200-11. doi: 10.2337/db16-0199
MAGIC insulin secretion during OGTT GWAS
Publications
A central role for GRB10 in regulation of islet function in man.
Prokopenko I, et al.
PLoS Genet. 2014 Apr 3;10(4):e1004235. doi: 10.1371/journal.pgen.1004235
MAGIC fasting proinsulin GWAS
Publications
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
Strawbridge RJ, et al.
Diabetes. 2011 Oct;60(10):2624-34. doi: 10.2337/db11-0415.
MAGIC 2010 HbA1c GWAS
Publications
Common variants at 10 genomic loci influence hemoglobin A1(C) levels via glycemic and nonglycemic pathways.
Soranzo N, et al.
Diabetes. 2010 Dec;59(12):3229-39. doi: 10.2337/db10-0502.
MAGIC two-hour glucose GWAS
Publications
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
Saxena R, Hivert M-F, et al.
Nat Genet. 2010 Feb;42(2):142-8. doi: 10.1038/ng.521.
MAGIC 2010 fasting glucose and insulin GWAS
Publications
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Dupuis J, et al.
Nat Genet. 2010 Feb;42(2):105-16. doi: 10.1038/ng.520.
MAGIC 2012 fasting glucose and insulin GWAS
Publication
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Manning AK, Hivert M-F, Scott RA, et al.
Nat Genet. 2012 May 13;44(6):659-69. doi: 10.1038/ng.2274.
Richards
Effector Index predicted effector genes
Type 2 diabetes predicted effector genes (Mahajan A and McCarthy MI, 2019)
Type 2 diabetes predicted effector genes
View predictions for:
Reference:
Mahajan A, McCarthy MI. Unpublished, 2019.