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EGL method - CARDIoGRAM

Submitted by mariacos on Wed, 05/26/2021 - 14:58
  • Read more about EGL method - CARDIoGRAM

To prioritize likely causal genes for each of 241 genomewide-significant CAD association signals, eight locus-based or similarity-based predictors of causal genes were considered:

AMP-T2D UCSD Diabetic Complications: East Asians

  • Read more about AMP-T2D UCSD Diabetic Complications: East Asians

Publications

Salem R, et al. (2021) Unpublished.

AMP-T2D UCSD Diabetic Complications: South Asians

  • Read more about AMP-T2D UCSD Diabetic Complications: South Asians

Publications

Salem R, et al. (2021) Unpublished.

AMP-T2D UCSD Diabetic Complications: Hispanics

  • Read more about AMP-T2D UCSD Diabetic Complications: Hispanics

Publications

Salem R, et al. (2021) Unpublished.

AMP-T2D UCSD Diabetic Complications: African Americans

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Publications

Salem R, et al. (2021) Unpublished.

Uganda Genome Resource pan-African GWAS

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Summary statistics are available for download from the GWAS Catalog.

Publications

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.
Gurdasani D, et al.
Cell. 2019 Oct 31;179(4):984-1002.e36. doi: 10.1016/j.cell.2019.10.004.ation
PMID:31675503

Middle Eastern Qatari population WGS

  • Read more about Middle Eastern Qatari population WGS

Summary statistics are available for download from the GWAS Catalog.

Publications

Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits.
Thareja G, Al-Sarraj Y, et al.
Nat Commun. 2021 Feb 23;12(1):1250. doi: 10.1038/s41467-021-21381-3.
PMID: 33623009

UKB and ICBP blood pressure GWAS

  • Read more about UKB and ICBP blood pressure GWAS

Summary statistics are available for download from the GWAS Catalog.

Publications

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelou E, et al.
Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x.
PMID:30224653

Heart rate and hypertension GWAS

  • Read more about Heart rate and hypertension GWAS

Summary statistics are available for download from the GWAS Catalog.

Publications

Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.
Zhu Z, et al.
Respir Res. 2019 Apr 2;20(1):64. doi: 10.1186/s12931-019-1036-8.
PMID:30940143

Coronary artery disease in Japan GWAS

  • Read more about Coronary artery disease in Japan GWAS

Summary statistics are available for download from the GWAS Catalog.

Publications

Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease.
Matsunaga H, et al.
Circ Genom Precis Med. 2020 Jun;13(3):e002670. doi: 10.1161/CIRCGEN.119.002670.
PMID:32469254

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