The Knowledge Portals can be used to help answer many different research questions. The pages listed below describe typical workflows, along with best practices for their use.
- Genetic support workflow: Do human genetic and genomic results provide evidence about the involvement of a gene of interest in a disease or trait?
- Multi-trait analysis workflow: Is a variant, gene, or genetic locus significantly associated with multiple traits?
- Rare variant gene-level associations workflow: What can custom computation of rare variant gene-level association statistics reveal about a variant or gene of interest?
- Integrative analysis workflow: What can I learn about potentially causal variants and genes in a locus by integrating genetic associations, credible sets, and multiple types of epigenomic annotations?