Thoracic aorta dimensions GWAS

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Summary statistics - ascending aorta diameter
Summary statistics - descending aorta diameter
README

Publications

Deep learning enables genetic analysis of the human thoracic aorta.
Pirruccello JP, et al.

Nat Genet. 2021 Nov 26. doi: 10.1038/s41588-021-00962-4.
PMID:34837083

Phenotypes

  • Ascending aorta diameter
  • Descending aorta diameter

Experiment summary

The study is an analysis of genetic associations for diameter of the aorta, which is linked to predisposition for aortic dissection. A deep learning model was trained to evaluate aortic images and was then applied to images for 33,420 individuals in the UK Biobank population to measure the diameter of the ascending and descending aorta.

 

Dataset ID
Pirruccello_2020_Aorta_diameter_eu