The Human Genetics Amplifier (HuGeAMP) is a software platform and infrastructure that aggregates, integrates, and analyzes human genetic and genomic data in order to spark insights into complex diseases.

The Knowledge Portal Network (KPN) is ecosystem of interconnected web portals that facilitate innovative and intuitive analysis and visualization of biomedical data. The Knowledge Portals that are based on human genetic association data, listed below, are powered by the HuGeAMP platform.

The Knowledge Portals:

  • aggregate comprehensive data relevant to diseases and traits;

  • harmonize and analyze the data;

  • represent the data in a way that helps researchers to distill meaning from them; and

  • provide interactive tools for custom analyses that access individual-level data in a secure manner.

We welcome new collaborations. Please contact us at


Portals on HuGeAMP

Common Metabolic Diseases Knowledge Portal
Visit portal
Cardiovascular Disease Knowledge Portal
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Cerebrovascular Disease Knowledge Portal
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Sleep Disorder Knowledge Portal
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Type 1 Diabetes Knowledge Portal
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Type 2 Diabetes Knowledge Portal
Visit portal
Musculoskeletal Knowledge Portal
Visit portal
ALS Knowledge Portal
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Lung Disease Knowledge Portal
Visit portal

Research Knowledge Portals

The APOL1 Portal
Visit portal
Lipid Droplet Knowledge Portal
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What's new

We're hosting an ancillary session at #ASHG2021 on genetic, epigenomic, and functional approaches to identifying effector genes for complex diseases.
Slides and video are now available from our Sept. 23, 2021 webinar describing the Common Metabolic Diseases Genome Atlas.

The Diabetes Epigenome Atlas is now the Common Metabolic Diseases Genome Atlas (CMDGA;! CMDGA has new data types relevant to multiple diseases in addition to diabetes, and offers beautiful new visualizations for gene expression and single-cell epigenomic data. Find out about this expanded and updated resource in this week's webinar.

Thursday, September 23
12-1 PM US Eastern time

Applications for AMP-CMD Opportunity Pool funding are now being accepted.