Life-course total body BMD GWAS


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Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Medina-Gomez C, et al.
Am J Hum Genet. 2018 Jan 4; 102(1): 88–102. doi: 10.1016/j.ajhg.2017.12.005


  • total body bone mineral density


Subjects Cohort Ancestry
3736 1982 Pelotas Mixed
8,165 ALSPAC European
1,885 BMDCS Mixed
2,789 BPROOF European
915 CHS_EA European
273 CHS_AA African American
271 COPSAC2000 European
446 COPSAC2010 European
90,298 deCode European
20,663 EPIC European
2,786 ERF European
1,357 Fenland GWAS European
8,994 Fenland-Omics European
8,481 FHS European
5,732 Generation R Mixed
938 GOOD European
2,658 HABC Mixed
5,130 MrOS-USA European
5,744 NEO STUDY European
993 OPRA European
2,215 ORCADES European
469 PANIC European
1,494 RAINE STUDY Mixed (mainly European)
6,291 RS1 European
2,157 RS2 European
3,048 RS3 European
3,625 SOF European
5,654 TwinsUK European
1,553 UK Biobank European


Genetic Factors for Osteoporosis (GEFOS) Consortium Learn more >

Experiment summary

This study analyzed genetic associations for total body bone mineral density (g/cm2), measured by dual-energy X-ray absorptiometry, in individuals of multiple ancestries.

contributing community
msk, mskkp, bone
Dataset ID