EGL method - richards

Submitted by dkjang on Mon, 07/13/2020 - 11:01

The Effector Index (Ei) algorithm calculates the probability of causality for each gene at a locus that harbors genome-wide significant SNVs for a disease or trait.

Full documentation is available in:
Forgetta V, Jiang L, Vulpescu NA, et al. An effector index to predict causal genes at GWAS loci. Submitted for publication, 2020.

IPF GWAS

Dataset

Download summary statistics here.

Publication

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.
Allen RJ, et al.
Am J Respir Crit Care Med 2020 Mar 1;201(5):564-574. doi: 10.1164/rccm.201905-1017OC.
PMID:31710517