Intracranial aneurysm GWAS: East Asians

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Publications

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.
Bakker MK, et al.
Nat Genet. 2020 Dec 1; 52(12): 1303–1313. doi: 10.1038/s41588-020-00725-7.
PMID:33199917

Phenotypes

  • intracranial aneurysm

Subjects

Note that all controls were unselected controls, with no intracranial aneurysm status known.

Cases Controls Cohort Ancestry
2,662 164,009 Biobank Japan East Asian
597 70,939 China Kadoorie Biobank East Asian

Experiment summary

The dataset described on this page represents a meta-analysis of intracranial aneurysm genetic associations from two East Asian cohorts. These results were also meta-analyzed with European-ancestry results, and the cross-ancestry meta-analysis is available as the "Intracranial aneurysm GWAS" dataset. The results of the European-only analysis are available in the "Intracranial aneurysm GWAS: Europeans" dataset.

Dataset ID
GWAS_IA-BakkerMK2020_ea