GIANT UK Biobank GWAS
Dataset
Download URL: https://www.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium_data_files
Note that BMI associations were downloaded from GIANT after the most recent update on June 25, 2018.
Download URL: https://www.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium_data_files
Note that BMI associations were downloaded from GIANT after the most recent update on June 25, 2018.
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Köttgen A, et al.
Nat Genet. 2013 Feb;45(2):145-54. doi: 10.1038/ng.2500
Download summary statistics at the GIANT Consortium website.
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, et al.
Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132
Summary statistics are available for download from the GIANT Consortium website.
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Graff M, et al.
PLoS Genet. 2017 Apr 27;13(4):e1006528. doi: 10.1371/journal.pgen.1006528
Download summary statistics at the GIANT Consortium website
FTO genotype is associated with phenotypic variability of body mass index.
Yang J, et al.
Nature. 2012 Oct 11;490(7419):267-72. doi: 10.1038/nature11401
Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice.
Chennamsetty I, et al.
Cell Rep. 2016 Oct 4;17(2):527-540. doi: 10.1016/j.celrep.2016.09.005
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.
Knowles JW, et al.
J Clin Invest. 2015 Apr;125(4):1739-51. doi: 10.1172/JCI74692
All samples in this dataset are included in the "DIAMANTE (European) T2D GWAS" dataset.
All samples in this dataset are included in the "DIAMANTE (European) T2D GWAS" dataset.
A genome-wide association meta-analysis identifies new childhood obesity loci.
Bradfield JP, et al.
Nat Genet. 2012 May;44(5):526-31. doi: 10.1038/ng.2247
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.
Salem RM, et al.
J Am Soc Nephrol. 2019 Oct;30(10):2000-2016. doi: 10.1681/ASN.2019030218