Major depressive disorder 2018 GWAS: European ancestry

Summary statistics are available for download from the GWAS Catalog.

Publications

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, et al.
Nat Commun. 2018 Apr 16;9(1):1470. doi: 10.1038/s41467-018-03819-3.
PMID: 29662059

Phenotypes

• Major depressive disorder

Experiment summary

This study analyzed genetic associations for "broad depression", defined as self-reported past help-seeking for problems with "nerves, anxiety, tension or depression" in 113,769 cases and 208,811 control subjects of European ancestry from the UK Biobank cohort.