ProDiGY 2021 GWAS: youth-onset T2D vs. youth controls, trans-ancestry

Publications

The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium.
Srinivasan S, et al.
Diabetes. 2021 Apr;70(4):996-1005. doi: 10.2337/db20-0443.
PMID:33479058

Phenotypes

  • Youth-onset type 2 diabetes

Project

ProDiGY is a multiethnic collaboration of three studies (TODAY, SEARCH, and T2D-GENES) with 3,006 youth case subjects with type 2 diabetes (mean age 15.1 ± 2.9 years) and 6,061 diabetes-free adult control subjects (mean age 54.2 ± 12.4 years).

Experiment summary

This study analyzed genetic associations with youth-onset type 2 diabetes (defined as T2D with an onset under 20 years of age) in a population of 3,006 youth subjects and 856 youth control subjects of Non-Hispanic White, African American, and Hispanic ancestries.

Dataset ID
Srinivasan2021_YouthT2D_YouthControl_Mixed