ALS 2021 GWAS: European ancestry

Summary statistics are available for download from the GWAS Catalog.

Publications

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
van Rheenen W, van der Spek RAA, Bakker MK, et al.
Nat Genet. 2021 Dec;53(12):1636-1648. doi: 10.1038/s41588-021-00973-1.
PMID:34873335

Phenotypes

• ALS

Experiment summary

This dataset is an analysis of genetic associations with amyotrophic lateral sclerosis (ALS) in a European-ancestry population of 27,205 ALS cases and 110,881 controls. The mixed-ancestry dataset including these subjects is also available in the Portal.