Liver enzyme 2021 GWAS

Summary statistics are available for download from the GWAS Catalog.

Publications

Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes.
Pazoki R, Vujkovic M, et al.
Nat Commun. 2021 May 10;12(1):2579. doi: 10.1038/s41467-021-22338-2.
PMID:33972514

Phenotypes

  • Alanine transaminase
  • Alkaline phosphatase
  • Gamma-glutamyl transferase

Experiment summary

This study analyzed genetic associations with serum levels of the liver enzymes alanine transaminase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) in UK Biobank participants of European ancestry.

Dataset ID
Pazoki_2021_liver_enzyme_EU