GLGC 2021 Lipids GWAS: trans-ancestry

Summary statistics are available for download from the Global Lipids Genetics Consortium.

Publications

The power of genetic diversity in genome-wide association studies of lipids.
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, et al.
Nature. 2021 Dec;600(7890):675-679. doi: 10.1038/s41586-021-04064-3.
PMID:34887591

Phenotypes

  • Total cholesterol
  • HDL cholesterol
  • LDL cholesterol
  • Triglycerides
  • Non-HDL cholesterol

Experiment summary

This dataset is a multi-ancestry meta-analysis of genetic associations with plasma lipid levels in more than 1.6 million participants, including 350,000 of non-European ancestry. Also available in the Portal are single-ancestry meta-analyses from this study for African, East Asian, European, Hispanic, and South Asian ancestries.

 

Dataset ID
Graham_2021_lipids_Mixed