The <i>APOL1</i> Portal: <em>Genomic data-sharing to empower efforts towards understanding and treating APOL1 associated kidney disease</em>

The APOL1 Portal enables browsing, searching, and analysis of human genetic and glomerular transcriptomic data related to APOL1 associated focal segmental glomerulosclerosis (FSGS), while protecting the integrity and confidentiality of the underlying information.

Publication

A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental glomerulosclerosis.
McNulty MT, et al.
Kidney Int. 2021 Dec 18:S0085-2538(21)01149-2. doi: 10.1016/j.kint.2021.10.041
PMID: 34929253

Three ways to explore the data:

1. Interactively explore transcriptomic & clinical data
2. Look up results for single genes
3. Interactively explore transcriptomic and clinical data, as diagrammed below:
   • Differential Expression
   • Genome-wide APOL1 Correlations
   • Differential Co-expression