CKDGen GWAS - UACR in Europeans

Dataset

All CKDGen GWAS datasets draw upon overlapping sample sets.

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Publications

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
Teumer A, et al.
Nat Commun. 2019 Sep 11;10(1):4130. doi: 10.1038/s41467-019-11576-0

Dataset phenotypes

  • urinary albumin-to-creatinine ratio

Dataset subjects

Samples Cohort Ancestry
4,052 Action in Diabetes and Vascular disease : preterAx and diamicroN mr Controlled Evaluation (ADVANCE) European
3,196 Age, Gene/Environment Susceptibility Study (AGES) European
729 Amish Studies (Amish) European
7,243 Atherosclerosis Risk in Communities study (ARIC) European
4,649 The Cooperative Health Research in South Tyrol (CHRIS) European
2,087 Cardiovascular Health Study (CHS) European
7,724 deCODE genetics/Amgen (DECODE) European
1,486 DIAbetes COhoRtE (DIACORE) European
2,425 Epidemiological investigation of the chances of preventing, recognizing early and optimally treating chronic diseases in an elderly population (ESTHER) European
6,523 The Framingham Heart Study (FHS) European
147 The Finnish Cardiovascular Study (FINCAVAS) European
4,950 German Chronic Kidney Disease study (GCKD) European
1,959 Generation R (Generation R) European
2,722 Cooperative Health Research in the Augsburg Region (KORA F3) European
2,915 Cooperative Health Research in the Augsburg Region (KORA F4) European
4,947 LIFE-Adult (LIFE-Adult) European
1,881 LIFE-Child (LIFE-Child) European
13,332 Lifelines Cohort Study (Lifelines) European
2,514 Multi-Ethnic Study of Atherosclerosis (MESA) European
494 Microisolates in South Tyrol (MICROS) European
13,660 MyCode Community Health Initiative (MyCode (Geisinger Research)) European
5,724 Netherlands Epidemiology of Obesity (NEO) European
733 Prospective Investigation of Vasculature in Uppsala Seniors (PIVUS) European
839 POPGEN control sample (POPGEN) European
3,634 Prevention of Renal and Vascular End-stage Disease study (PREVEND) European
2,861 Rotterdam Study (RS-III) European
3,199 Study of Health in Pomerania (SHIP) European
985 Study of Health in Pomerania - Trend (SHIP-Trend) European
934 Swiss Kidney project for genes in hypertension (SKIPOGH) European
950 Sorbs cohort (Sorbs) European
436,392 UK (United Kingdom) Biobank (UKBB) European
620 Uppsala study of adult men (ULSAM) European
301 Vanderbilt BioVU (Vanderbilt-660) European
423 Vanderbilt BioVU (Vanderbilt-Omni1) European
131 Vanderbilt BioVU (Vanderbilt-Omni5) European

Project

The Chronic Kidney Disease Genetics Consortium (CKDGen) is a consortium of researchers investigating genetic loci associated with kidney function and disease.

 

 

 

Experiment summary

Summary meta-analysis data are provided for urinary albumin-to-creatinine ratio. All subjects in this analysis were of European ancestry. These subjects are also included in the dataset "CKDGen GWAS - UACR associations".

Dataset ID
GWAS_CKDGenConsortiumUACR_eu