Publication
Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations.
Salo V, Määttä J, Sliz E, et al.
Nature Communications. 2024 Nov 7;15(1):9424. doi: 10.1038/s41467-024-53467-z.
PMID: 39511132
Phenotypes
- Lumbar disc herniation
Experiment summary
This study performed a genome-wide association analysis of lumbar disc herniation in 80724 cases and 748975 controls from a European cohort across three large biobanks (FinnGen, Estonian Biobank, UK Biobank) and performed a meta-analysis combining results, identifying multiple associated loci and expanding the genetic architecture of disc herniation.
Dataset ID
Salo2024_LumDiscHer_EU