Summary statistics are available for download from the GWAS Catalog.
Publication
Rare genetic associations with human lifespan in UK Biobank are enriched for oncogenic genes.
Park J, Peña-Tauber A, Talozzi L, Greicius MD, Le Guen Y.
Nature Communications. 2025 Feb 28;16(1):2064. doi: 10.1038/s41467-025-57315-6.
PMID: 40021682
Phenotypes
- Aging/ Human lifespan (age-at-death / survival)
Experiment summary
This study performed survival GWAS in 180970 male UK Biobank European-ancestry participants using age-at-death and last-known-age, identifying common-variant signals and indicating cancer-driven influences on lifespan.
Dataset ID
Park2025_Life_Span_Male_EU