Summary statistics are available for download from the GWAS Catalog.
Publication
Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction.
Braun A, Shekhar S, Levey DF, et al.
Nature Communications. 2024 Nov 13;15(1):9839. doi: 10.1038/s41467-024-53595-6.
PMID: 39537604
Phenotypes
- Myasthenia gravis (overall)
Experiment summary
This genome-wide meta-analysis of myasthenia gravis included 5,708 cases and 432,028 controls of European ancestry with replication in 3,989 cases and 226,643 controls (23andMe), identifying 12 independent signals across 11 loci and demonstrating subtype-specific associations for early- and late-onset MG, as well as potential for polygenic prediction.
Dataset ID
Braun2024_Myasthenia_Gravis_EU