Summary statistics are available for download from the GWAS Catalog.
Publication
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, et al.
Nature Neuroscience. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7.
PMID: 30718901
Phenotypes
- Major depressive disorder (MDD)
- Depression
Experiment summary
This study meta-analyzed depression GWAS across 170756 cases and 329443 controls of European ancestry, identifying 102 independent variants, 269 genes, and 15 gene sets with enrichment in prefrontal brain regions.
Dataset ID
Howard2019_MDD_EU