Major depressive disorder 2018 GWAS: European ancestry

Summary statistics are available for download from the GWAS Catalog.

Publication

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, et al.
Nature Communications. 2018 Apr 16;9(1):1470. doi: 10.1038/s41467-018-03819-3.
PMID: 29662059

Phenotypes

  • Broad depression
  • Probable major depressive disorder (MDD)
  • ICD-9/ICD-10-coded MDD

Experiment summary

This study analyzed genome-wide associations for three depression-related phenotypes in UK Biobank and identified loci implicating excitatory synaptic pathways using 322580 total participants of European ancestry.

Dataset ID
Howard2018_MDD_EU