Summary statistics are available for download from the CKDGen consortium.
Publications
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements
Scholz M et al.
Nat Commun. 2024 Jan 18;15(1):586. doi: 10.1038/s41467-024-44709-1.
PMID: 38233393
Phenotypes
- Blood urea nitrogen
- Chronic kidney disease (CKD)
- eGFRcreat (serum creatinine)
- Gout
- Macroalbuminuria vs. controls
- Uric acid
- Urinary albumin-to-creatinine ratio (UACR)
Experiment summary
This study was a trans-ancestry meta-analysis of X chromosome genetic associations for kidney function traits in up to 908,697 individuals. Note that the study did not control for diabetes status and some subjects had diabetes.
Dataset ID
Scholz2024_KidneyFunction_Mixed