GIANT 2018 Body Fat Distribution exome chip analysis

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Publications

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Justice AE, et al.
Nat Genet. 2019 Mar;51(3):452-469. doi: 10.1038/s41588-018-0334-2

Phenotypes

  • Waist-hip ratio adj BMI

Project

Genetic Investigation of ANthropometric Traits (GIANT) consortium Learn more >

GIANT is an international collaboration that seeks to identify genetic loci that modulate human body size and shape, including height and measures of obesity.

Experiment summary

This study is a meta-analysis of genetic associations with waist-hip ratio adjusted for BMI, a measure of body fat distribution, in over 344,000 individuals across 5 ancestries. Subset datasets are available in the Portal for females, males, Europeans, European females, and European males.

Dataset ID
ExChip_GIANTwWHR