Summary statistics are available for download from the authors.
Publications
Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging.
Timmers PRHJ, et al.
Nat Aging. 2022 Jan;2(1):19-30. doi: 10.1038/s43587-021-00159-8. Epub 2022 Jan 20.
PMID: 37118362
Phenotypes
- Aging-GIP1 principal component
- Aging-GIP1 principal component adj socioeconomic status
Experiment summary
This study analyzed genetic associations for the first principal component (aging-GIP1) from a combined analysis of genetic association studies for healthspan, father and mother lifespan, exceptional longevity, frailty index and self-rated health, in 195,015 particilants of European ancestry. The results were either unadjusted or adjusted for socioeconomic status.
Dataset ID
Timmers2022_AgingGIP1_EU