Esophageal disease 2021 GWAS: European ancestry

Summary statistics are available for download from the GWAS Catalog.

Publications

Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis.
Ong J-S, et al.
Gut. 2022 Jun;71(6):1053-1061. doi: 10.1136/gutjnl-2020-323906.
PMID: 34187846

Phenotypes

  • Gastroesophageal reflux disease (GERD)
  • Barrett's esophagus

Experiment summary

This study analyzed genetic associations for GERD and Barrett's esophagus in 129,080 cases and 473,524 controls of European ancestry.

Dataset ID
Ong2021_GERD_EU