New effector gene predictions available for stroke and eGFRcrea

The latest additions to our collection of effector gene lists for common diseases are lists for potential stroke and creatinine-based estimated glomerular filtration rate (eGFRcrea) effector genes. To generate the lists, each group of authors began with the significant loci from large GWAS and then used a variety of bioinformatic methods to prioritize genes at each locus.

The list of predicted stroke effectors, generated by the GIGASTROKE consortium (Mishra, Malik, Hachiya et al., 2022), is based on a GWAS for stroke in more than 1.6 million individuals.

The list of predicted eGFRcrea effector genes, generated by members of the CKDGen consortium (Stanzick et al., 2021), is based on a GWAS for eGFRcrea with over 1.2 million subjects.

Please check out these interactive interfaces and let us know what you think!

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