Ascending aorta function predicted effector genes

Ascending aorta function predicted effector genes

View predictions for:

• Ascending aorta function

Method:

Genes were prioritized at loci genetically associated with three aortic properties, based on three evidence types: results from DEPICT (Data-driven Expression Prioritized Integration for Complex Traits); presence of a coding variant in high LD with the lead SNP; and proximity of a gene to the lead SNP (nearest gene).

Reference:

Genomic insights in ascending aortic size and distensibility.
Benjamins JW, et al.
EBioMedicine. 2022 Jan;75:103783. doi: 10.1016/j.ebiom.2021.103783.
PMID: 34968759