Cardiometabolic trait predicted effector genes
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Method
Candidate causal genes for cardiometabolic traits were predicted by integration of genetic association results, expression and splicing quantitative trait loci (eQTLs and sQTLs), transcriptional regulation by physiological and pharmacological cardiometabolic regulators, and protein-protein interaction networks.
Reference:
Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes.
Gloudemans MJ, Balliu B, et al.
Genome Med. 2022 Mar 15;14(1):31. doi: 10.1186/s13073-022-01036-8.
PMID: 35292083
Portals
md, t2d, cvd, msk, nage, a2f, ocular
Weight
0
Phenotype groups
Cardiometabolic trait predicted effector genes (Gloudemans MJ et al., 2022)