ALS 2021 GWAS

Summary statistics are available for download from the GWAS Catalog.

Publications

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
van Rheenen W, van der Spek RAA, Bakker MK, et al.
Nat Genet. 2021 Dec;53(12):1636-1648. doi: 10.1038/s41588-021-00973-1.
PMID:34873335

Phenotypes

  • ALS

Experiment summary

This dataset is an analysis of genetic associations with amyotrophic lateral sclerosis (ALS) in a mixed-ancestry population of 29,612 ALS cases and 122,656 controls. The European-ancestry subset is also available in the Portal.

Dataset ID
vanRheenen_2021_ALS_Mixed