Download summary statistics (see file descriptions in the README):
KP.Format.ThumbOA.gwama.plotting.gz.minus9sout.gz
KP.Format.TKR.gwama.plotting.gz.minus9sout.gz
KP.Format.TJR.gwama.plotting.gz.minus9sout.gz
KP.Format.THR.gwama.plotting.gz.minus9sout.gz
KP.Format.SpineOA.gwama.plotting.gz.minus9sout.gz
KP.Format.KneeOA.gwama.plotting.gz.minus9sout.gz
KP.Format.KneeHipOA.gwama.plotting.gz.minus9sout.gz
KP.Format.HipOA.gwama.plotting.gz.minus9sout.gz
KP.Format.HandOA.gwama.plotting.gz.minus9sout.gz
KP.Format.GO.RAW.final.meta.results.Early_AllOA.txt.gz
KP.Format.GO.FILTER.GW.ThumbOA.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.TKR.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.TJR.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.THR.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.SpineOA.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.KneeOA.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.KneeHipOA.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.HipOA.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.HandOA.FULL.09052019.txt.gz
KP.Format.GO.FILTER.GW.AllOA.FULL.09052019.txt.gz
KP.Format.FingerOA.gwama.plotting.gz.minus9sout.gz
KP.Format.AllOA.gwama.plotting.gz.minus9sout.gz
Summary statistics and README for all samples except UK Biobank participants (all phenotypes)
Publications
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Boer CG, Hatzikotoulas K, Southam L, et al.
Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003
PMID: 34450027
Phenotypes
- Any osteoarthritis
- Finger osteoarthritis
- Hand osteoarthritis
- Hip osteoarthritis
- Knee and-or hip osteoarthritis
- Knee osteoarthritis
- Spine osteoarthritis
- Thumb osteoarthritis
- Total knee replacement
- Total knee and-or hip replacement
- Total hip replacement
Project
The Genetics of Osteoarthritis (GO) Consortium is a global collaboration between all available studies with the aim of understanding the genetics of ostoarthritis and related traits.
Experiment summary
This study is a meta-analysis of genetic associations for osteoarthritis performed across 13 cohorts of European and East Asian ancestry. Companion datasets in the Portal from the same publication include Genetics of Osteoarthritis (GO) Consortium GWAS, sex-specific analysis and Genetics of Osteoarthritis (GO) Consortium early-onset osteoarthritis GWAS.