Dataset
Summary statistic files are available for download from the GIANT consortium website.
Publications
Genome-wide Association Study of Body Fat Distribution Identifies Adiposity Loci and Sex-Specific Genetic Effects.
Rask-Andersen M, et al.
Nat Commun 2019 Jan 21;10(1):339. doi: 10.1038/s41467-018-08000-4.
PMID:30664634
Dataset phenotypes
- Arm fat ratio
- Leg fat ratio
- Trunk fat ratio
Dataset subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 55,006 | UK Biobank | European |
Project
Genetic Investigation of ANthropometric Traits (GIANT) consortium Learn more >
GIANT is an international collaboration that seeks to identify genetic loci that modulate human body size and shape, including height and measures of obesity.
Experiment summary
This study determined genetic associations for three measures of body fat distribution among UK Biobank participants. Using data from segmental body composition scans that estimate of the fat content of the trunk, arms and legs, GWAS were performed for the proportion of body fat present in each of these locations.