Lung function GWAS: UK Biobank

Dataset

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Publications

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Shrine N, et al.
Nat Genet. 2019 Mar;51(3):481-493. doi: 10.1038/s41588-018-0321-7

Dataset phenotypes

• Forced expired volume in 1 second (FEV1)
• Forced vital capacity (FVC)
• FEV1 to FVC ratio
• Peak expiratory flow

Dataset subjects

Experiment summary

This study analyzed genetic associations for 4 measures of lung function in over 300,000 subjects from the UK Biobank population.