Publications
An effector index to predict target genes at GWAS loci.
Forgetta V, Jiang L, Vulpescu NA, et al.
Hum Genet. 2022 Feb 11. doi: 10.1007/s00439-022-02434-z.
PMID: 35147782
Dataset phenotypes
- Calcium
- Bilirubin
- Random glucose
- LDL cholesterol
- Triglycerides
Experiment summary
This study analyzed genetic associations in UK Biobank participants. Single-gene mutations are known to affect each of the 5 phenotypes analyzed, providing a positive-control set of effector genes for that trait. These positive-control sets were used in the development of a method to identify putative effector genes for a given phenotype.
Dataset ID
GWAS_PredCausGen_eu