Dataset
Download summary statistics from GWAS Catalog.
Publications
Identification of New Therapeutic Targets for Osteoarthritis Through Genome-Wide Analyses of UK Biobank Data.
Tachmazidou I, et al.
Nat Genet. 2019 Feb; 51(2): 230–236. doi: 10.1038/s41588-018-0327-1
PMID:30664745
Dataset phenotypes
- Any osteoarthritis
- Knee and/or hip osteoarthritis
- Hip osteoarthritis
- Knee osteoarthritis
Dataset subjects
| Cases | Controls | Cohort | Ancestry |
|---|---|---|---|
| 70,532 (any OA) | 369,983 | UK Biobank | European |
| 6,520 (hip and/or knee OA) | 0 | Arthritis Research UK Osteoarthritis Genetics (arcOGEN) | European |
| 0 | 8,186 | United Kingdom Household Longitudinal Study (UKHLS) | European |
Experiment summary
This study is a meta-analysis of associations for four osteoarthritis phenotypes in UK Biobank and arcOGEN cohorts.
Accessing UK Biobank-arcOGEN osteoarthritis GWAS Meta-analysis results
UK Biobank-arcOGEN osteoarthritis GWAS Meta-analysis results are available at these locations:
- On Gene Pages in the Top variants and High-impact variants tables and in LocusZoom plots, for the phenotypes listed above
- On Variant Pages in the Associations at a glance section, the Association statistics across traits table, and in LocusZoom plots
- Via the Variant Finder tool
- From the "Explore by phenotype" search on the home page: first select a phenotype listed above, and then on the resulting page, select the UK Biobank-arcOGEN osteoarthritis GWAS Meta-analysis.
Dataset ID
GWAS_Osteoarthritis_eu