Publications
Genome-wide Association Study of Change in Fasting Glucose Over Time in 13,807 Non-Diabetic European Ancestry Individuals.
Liu CT, et al.
Sci Rep. 2019; 9: 9439. doi: 10.1038/s41598-019-45823-7
PMID:31263163
Phenotypes
- Fasting glucose change over time
Subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 695 | Busselton Health Study (BHS) | European |
| 1,408 | Cohort Lausannoise (COLAUS) | European |
| 716 | Data from an Epidemiological Study on the Insulin Resistance syndrome (DESIR) | European |
| 1,865 | Erasmus Rotterdam Health Study (ERGO) | European |
| 2,974 | Framingham Heart Study (FHS) | European |
| 689 | Helsinki Birth Cohort Study (HBCS) | European |
| 799 | Cooperative Health Research in the Region of Augsburg (KORA) | European |
| 1,142 | Prevention of renal and vascular end-stage disease (PREVEND) | European |
| 3,519 | SardiNIA Study on Aging (SARDINIA) | European |
Project
MAGIC (the Meta-Analyses of Glucose and Insulin-related traits Consortium) represents a collaborative effort to combine data from multiple GWAS to identify additional loci that impact on glycemic and metabolic traits.
Experiment summary
This study is a GWAS of longitudinal fasting glucose changes in up to 13,807 non-diabetic individuals of European descent from nine cohorts. Fasting glucose change over time was defined as the slope of the line defined by multiple fasting glucose measurements obtained over up to 14 years of observation.
Dataset ID
GWAS_MAGICwFGo_eu