IAMDGC 2013 AMD GWAS

Dataset

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Publications

Seven New Loci Associated With Age-Related Macular Degeneration.
Fritsche LG, et al.
Nat Genet. 2013 Apr; 45(4): 433–439e2.
PMID:23455636

Dataset phenotypes

  • Age-related macular degeneration
  • Neovascular age-related macular degeneration
  • Geographic atrophy

Dataset subjects

Cases Controls Cohort Ancestry
963 4,262 AMD-Europe-Johns Hopkins University(AMD-EU-JHU) European
103 1,052 Blue Mountains Eye Study (BMES) European
721 33,463 deCODE AMD European
317 1,636 Frankonian AMD study/Kooperative Gesundheitsforschung in der Region Augsburg Study (FAS/KORA) European
827 3,323 Japanese Age Related Eye Disease Study (JAREDS) East Asian
71 76 Massachusetts Eye and Ear Institute (MEEI) Sibpairs European
49 49 Melbourne AMD GWAS European
867 689 Miami/Vanderbilt  
1,464 1,150 Michigan/Mayo Clinic/AREDS/UPENN (MMAP)  
192 1,887 Rotterdam Study European
912 1,679 Tufts Medical Center/Massachusetts General Hospital (Tufts/MGH) European
161 260 UCSD GA Study  
150 601 UK Cambridge/Edinburgh Study 300k platform European
743 1,598 UK Cambridge/Edinburgh Study 550k platform European
110 119 Vision Research Foundation (VRF, India) South Asian

Project

IAMDGC logo

The International Age-related Macular Degeneration Genomics Consortium (originally the AMD Gene Consortium) was formed in early 2010 by 18 research groups from across the world, with support from the National Eye Institute, in order to analyze the genetic architecture of age-related macular degeneration.

Experiment summary

IAMDGC 2013 AMD GWAS is a meta-analysis combining data for >7,600 age-related macular degeneration (AMD) cases with advanced disease (geographic atrophy, neovascularization, or both) and >50,000 controls.

Dataset ID
GWAS_AMDGen