Bone size GWAS

Dataset

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Publications

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.
Styrkarsdottir U, et al.
Nat Commun. 2019 May 3;10(1):2054. doi: 10.1038/s41467-019-09860-0

Dataset phenotypes

  • Total hip area
  • Femoral neck area
  • Trochanter area
  • Intertrochanteric-shaft area
  • Lumbar spine area

Experiment summary

This study analyzed genetic associations with bone area, as measured by dual-energy X-ray absorptiometry (DXA) scans, for the hip, its sub-regions femoral neck, trochanter, and intertrochanteric/shaft, and for the lumbar spine.

Accessing Bone size GWAS results

Bone size GWAS results are available at these locations:

  • On Gene Pages in the Top variants and High-impact variants tables and in LocusZoom static plots, for the phenotypes listed above
  • On Variant Pages in the Associations at a glance section, the Associations across all datasets table, and in LocusZoom static plots
  • Via the Variant Finder tool
  • From the Explore by phenotype search on the home page: first select one of the phenotypes listed above and then on the resulting page, select the Bone size GWAS dataset.
Dataset ID
GWAS_DeCODE_eu