Publication
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies.
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Cell. 2025 Feb 6;188(3):640-652.e9. doi: 10.1016/j.cell.2024.12.002.
PMID: 39814019
Phenotypes
- Major depressive disorder (MDD)
- Depression
Experiment summary
This study conducted a trans-ancestry genome-wide association analysis of major depressive disorder across multiple cohorts including 27,487 cases and 52,648 controls, identifying 697 associations and highlighting implicated cell types and potential pharmacotherapies.
Dataset ID
PGC2025_MDD_EU