Dataset
Download full summary statistics | Download README
Download summary statistics minus UK Biobank samples and README
Publications
Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure.
Shah S, Henry A, et al.
Nat Commun. 2020 Jan 9;11(1):163. doi: 10.1038/s41467-019-13690-5.
Dataset phenotypes
- Heart failure
Project
The Heart Failure Molecular Epidemiology for Therapeutic Targets (HERMES) consortium is an international collaboration that aims to generate insights into the causal pathways leading to heart failure to inform new therapeutic approaches.
Experiment summary
This study was a GWAS meta-analysis for genetic associations with heart failure, a clinical syndrome defined by fluid congestion and exercise intolerance due to cardiac dysfunction. The complete summary statistics include 47,309 heart failure cases and 930,014 controls. The summary statistics minus UK Biobank samples include 40,805 cases and 542,362 controls (583,167 individuals total).