CMR-derived left ventricular measurements 2023 GWAS: European ancestry

Summary statistics are available for download from the GWAS Catalog.

Publication

Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy
Ning C et al.
Nat Commun. 2023 Nov 30;14(1):7900. doi: 10.1038/s41467-023-43771-5.
PMID: 38036550

Phenotypes

  • Dilated cardiomyopathy, strict definition
  • Hypertrophic cardiomyopathy
  • Left ventricular end systole inferoseptal wall thickness
  • Left ventricular end systole inferior wall thickness
  • Left ventricular end systole inferolateral wall thickness
  • Left ventricular end systole anterolateral wall thickness
  • Left ventricular end systole anterior wall thickness
  • Left ventricular end systole anterospetal wall thickness
  • Left ventricular end diastole inferoseptal wall thickness
  • Left ventricular end diastole inferior wall thickness
  • Left ventricular end diastole inferolateral wall thickness
  • Left ventricular end diastole anterolateral wall thickness
  • Left ventricular end diastole anterior wall thickness
  • Left ventricular end diastole anterospetal wall thickness
  • PulmonaryHT

Experiment summary

This study analyzed genetic associations for left ventricle imaging-derived phenotypes in 42,194 individuals from the UK Biobank with cardiac magnetic resonance (CMR) imaging.

Dataset ID
Ning2023_LeftVentricle_EU