MRI-derived body composition 2022 GWAS: European ancestry

Summary statistics are available for download from the GWAS Catalog.

Publication

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
van der Meer D et al.
Commun Biol. 2022 Nov 19;5(1):1271. doi: 10.1038/s42003-022-04237-4.
PMID: 36402844

Phenotypes

  • Abdominal fat ratio
  • Abdominal subcutaneous adipose tissue volume
  • Anterior thigh muscle volume
  • Anterior thigh muscle fat infiltration percentage
  • Liver proton density fat fraction
  • Posterior thigh muscle volume
  • Posterior thigh muscle fat infiltration percentage
  • Total thigh muscle volume z-score
  • Visceral adipose tissue volume
  • Weight-to-muscle ratio

Experiment summary

This study analyzed genetic associations for body composition traits in up to 32,970 individuals of European ancestry.

Dataset ID
vanderMeer2022_LiverFat_EU