Posterior urethral valves 2022 GWAS: trans-ancestry

Summary statistics are available for download from the GWAS Catalog.

Publications

Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves.
Chan MMY, et al.
Elife. 2022 Sep 20;11:e74777. doi: 10.7554/eLife.74777.
PMID: 36124557

Phenotypes

  • Posterior urethral valves

Experiment summary

This study was a trans-ancestry analysis of genetic associations for posterior urethral valves (PUV), which are a common cause of end-stage renal disease in children, in 132 unrelated male PUV cases and 23,727 controls.

Dataset ID
Chan2022_PUV_Mixed